LM Wavelens

Enhancing Light Sheet Microscopy with Wavelens: A Next-Generation Solution for Precision Imaging and Versatile Applications

When Wavelens is integrated into a light sheet microscope, it creates a next-generation system, with a competitive advantage in aberration-free modular illumination, tissue penetration depth and rivaling competitors in image resolution. Additionally, our technology can be made compatible (with several benefits) with other microscopy techniques, allowing the creation of a versatile microscope with more capabilities for users.

Additionally, our technology can be made compatible (with several benefits) with other microscopy techniques, allowing the creation of a versatile microscope with more capabilities for users. Kymatonics with the prototype Wavelens offers a competitive solution for precision light control suitable for application in a variety of fields. Wavelens, integrates conventional optical elements with a photonic structure that introduces controlled light scattering and an active optical element that shapes the wavefront (i.e. a spatial light modulator – SLM) to exploit increased optical paths. Microscopy is the flagship application of Wavelens, where it has been introduced in a light sheet microscopy prototype.

Currently, we have conducted initial measurements on artificial tissue samples and biological models with a prototype microscope where Wavelens has been integrated to evaluate its functional characteristics, and we are in the process of further maturing the technology, always guided by user needs.

When Wavelens is integrated into a light sheet microscope, it creates a next-generation system, with a competitive advantage in aberration-free modular illumination, tissue penetration depth and rivaling competitors in image resolution. Additionally, our technology can be made compatible (with several benefits) with other microscopy techniques, allowing the creation of a versatile microscope with more capabilities for users.

Additionally, our technology can be made compatible (with several benefits) with other microscopy techniques, allowing the creation of a versatile microscope with more capabilities for users. Kymatonics with the prototype Wavelens offers a competitive solution for precision light control suitable for application in a variety of fields. Wavelens, integrates conventional optical elements with a photonic structure that introduces controlled light scattering and an active optical element that shapes the wavefront (i.e. a spatial light modulator – SLM) to exploit increased optical paths. Microscopy is the flagship application of Wavelens, where it has been introduced in a light sheet microscopy prototype.

Currently, we have conducted initial measurements on artificial tissue samples and biological models with a prototype microscope where Wavelens has been integrated to evaluate its functional characteristics, and we are in the process of further maturing the technology, always guided by user needs.


Precision illumination with Wavelens		– Precision control of optical paths for enhanced stability
– Diffraction tolerant light sheet in turbid media up to a depth of 5 TMFPs
– Super apochromaticity within a spectral and focal range of: 400nm-1000nm and 0.1mm-50mm
Illumination specs– Laser sources at five wavelengths (488nm, 520nm, 593nm, 632nm, 730nm)
– Brightfield detection with white light illumination (LED source) to locate sample
Light sheet specifications (@520nm)– Light sheet generated by Wavelens
– Variable light sheet thicknesses (FWHM): 400nm – 2.5μm
– User defined working distances of 1mm – 5cm
Modularity of operation– Reduced optical components (e.g., objectives) and mechanical parts
– Small form factor, reduced effect of light source quality, optical aberrations correction
– Small light sheet width fluctuations: 0.97±0.05μm over a WD = 5-7mm
– Operation in a wide range of specimen environmental conditions, i.e., air, water, gel, cell culture media, or optical clearing materials if necessary